Abstract
Synthesis and conformational studies of a short linear peptide containing a pyrrole amino acid ( 1, Paa) and a furan amino acid ( 2, Faa), namely Boc-hGly-Faa- d-Pro-Gly-Paa-hGly-Faa-OMe ( 3), were carried out in which it was established that peptide 3 adopted a well-defined β-hairpin structure in DMSO- d 6.
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