Novel electrochemical non-enzymatic glucose sensor based on 3D Au@Pt core–shell nanoparticles decorated graphene oxide/multi-walled carbon nanotubes composite

Abstract

A novel carbon composite was integrated with Au@Pt core–shell nanoparticles (Au@Pt NPs) to construct a sensing interface for enzyme-free electrochemical detection of glucose. As surfactant, graphene oxide (GO) was used to disperse multi-walled carbon nanotubes (MWCNTs). After the glassy carbon electrode (GCE) was modified with the mixture of GO and MWCNTs, the Au@Pt NPs were decorated on it. The prepared novel three-dimensional sensor interface was applied to detect glucose without enzyme at a remarkable negative potential (at about −0.013 V vs. Ag/AgCl), demonstrating a low detection limit (4.2 × 10−8 M) and two wide linear range from 5 × 10−8 to 1 × 10−4 M and 1 × 10−4 M to 2.5 × 10−3 M. In addition, the non-enzymatic glucose sensing platform can be realized for practical application.