Abstract

 CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
 The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
 This review assesses immunoglobulin human and recombinant human hyaluronidase (HyQvia) as a solution for subcutaneous infusion, available in the following strengths:
 
 normal immunoglobulin (human) 10%: 2.5 g/25 mL, 5 g/50 mL, 10 g/100 mL, 20 g/200 mL, 30 g/300 mL
 recombinant human hyaluronidase: 200 units/1.25 mL, 400 units/2.5 mL, 800 units/5 mL, 1,600 units/10 mL and 2,400 units/15 mL
 
 
 Indication: As replacement therapy for primary humoral immunodeficiency and secondary humoral immunodeficiency in adult patients.
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