Abstract
Nonsecretory multiple myeloma (NSMM) is a rare subtype of mutiple myeloma (MM). MM is normally associated with the secretion of monoclonal Ig (M spike) detected by serum or urine immunofixation/ electrphoresis; however in NSMM an M spike is not dedected, thus leading to either a misdiagnosis or a delayed diagnosis. A recent method of assessment for plasma cell disorders, serum free light chain assay (SFLC), individuates cases with measurable amounts of FLC, i.e., oligosecretory multiple mieloma (OSMM) or FLC-MMs.
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