Abstract
Abstract In this study we implemented depolarization on whole blood samples of 20 adult breast cancer patients as well as 20 normal healthy persons and recorded Mueller matrix based polarization parameters. The most useful polarization parameter on the basis of which we can distinguish the breast cancer disease from normal is depolarization index. We have used a wavelength range of light from 400 to 800 nm wavelength at a fixed transmission window of 0.18 - 0.19 for all the samples. In case of Breast cancer 90% – 70% light is depolarized in the spectral range of 420 – 480 nm. For normal blood less light is depolarized i.e., 78% – 55%. For second spectral range 500 – 560 nm measure depolarization index is 23% – 20% for breast cancer but 15% – 14% for normal blood. Similarly, other polarization parameters like linear retardence, circular retardence, and linear diattenuation for breast cancer differ from normal blood samples.
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