Abstract
Day-old White Leghorn chicks were fed P. citrinum-contaminated corn at 3.88, 7.75, 31, or 62% levels in the ration for a period of 5 weeks. High treatment levels (31 and 62%) of contaminated corn in the ration caused severe growth depression, high mortality, and significant decreases in feed consumption. Necrosis of periportal and centrilobular hepatocytes, glomerular atrophy and hyperplasia, degeneration and necrosis of tubular epithelial cells, lymphoid depletion, suppression of hematopoiesis, necrosis of pancreatic acinar cells, and a cardiac and skeletal myopathy were observed microscopically in chicks fed 31 and 62% contaminated corn in the rations. Low levels of contaminated corn in the ration (3.88 and 7.75%) caused few clinical effects; however, liver and kidney changes were observed microscopically. Ultrastructural observation of affected tissues showed swelling of mitochondria, dilatation of the endoplasmic reticulum, increased numbers of autophagic vacuoles and paramyelin figures, and lipoprotein peroxidation of organelles. The toxin (s) present in the P. citrinum contaminated ration have not been identified.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
