Abstract
Introduction: Idiopathic Granulomatous Mastitis; Despite its low incidence, is in high interest due to masquerading as carcinoma of the breast. In confirmed IGM case series, it`s been reported that more than 50% of patients were initially misdiagnosed as affecting by carcinoma of the Breast. Herein we are introducing a non-surgical management of IGM with frequently aspiration of the masses accompanied by using bacteriostatics and close regular surveillance. Material and Method: This was a before and after clinical trial looking at the effects of repeated aspirations coupled with antibiotic treatment on the natural course of IGM. Overall 55 patients met the inclusion criteria. These patients underwent clinical and imaging study as well as Core Needle Biopsy (CNB) of the lesion with a 14-16 Gauge needle. Patients` presenting sign and symptoms were categorized into six variable ones, including inflammation, Erythma, mass, pain and sinus formation. Confirmed cases of IGM were treated with antibiotic therapy (Ciprofloxacin 500 mg, or Trimethoprin-Sulfamethoxazol 400+80 mg every 12 hours) until either the relief of symptoms or a maximum of 3 weeks. One or two Weeks follow up visits were conducted in the first three months, monthly visits in the first six months, and then no matter when the last visit was done, it was recorded. Results: 44 patients (80% of cases), elucidated signs of inflammation, whereas solely 18 patients (32% of cases) were presented with inflamed breasts at final visit. (P value=0.03) 45 patients (81% of cases) presenting symptom was erythema, ultimately there were 14 cases (25%) in whom erythema persists. (p value=0.03) Mass presence was the dominant sign being discovered in 45 (72%) of enrolled cases at the time of first visit. The reported results has experienced a decline curve, finally 10 cases (18%) has remained symptomatic with a mass. (P value=0.02) Furthermore pain was elucidated in more than half of those who entered the study, 25 cases (56%). Sinus formation has complicated 14.5% (8 cases) of the patients, interestingly followed by a minimal rise at second visit during 1-3 weeks, the number of affected patients was consistently reported as 7 patients (12%) during the further visits. Discussion and Conclusion: Because of the nature of the disease which is an inflammatory reaction, any form of surgical intervention will be an unsuitable procedure and may become a disaster for both patient and the physician. As a result, the procedure of recurrent drainage may resolve the symptoms of pain, erythema and possibly the sinus formation, ultimately the mass will be resolved; therefore the recurrent drainage is highly recommended.
Highlights
Idiopathic Granulomatous Mastitis; Despite its low incidence, is in high interest due to masquerading as carcinoma of the breast
The procedure of recurrent drainage may resolve the symptoms of pain, erythema and possibly the sinus formation, the mass will be resolved; the recurrent drainage is highly recommended
Nonneoplastic chronic inflammatory disease of the breast [1]. This selflimiting, non-case eating benign disorder known as Idiopathic Granulomatous Lobular Mastitis, a breast disease of unknown etiology that was first described by Kessler and Wolloch in 1972 [2,3]
Summary
Idiopathic Granulomatous Mastitis; Despite its low incidence, is in high interest due to masquerading as carcinoma of the breast. The misery of affecting by Breast cancer, leads to one of the most common cause of surgical clinic referrals by women. Idiopathic Granulomatous Mastitis; Despite its low incidence, is in high interest due to masquerading as carcinoma of the breast though finalizing an appropriate management is crucial. It is a rare, nonneoplastic chronic inflammatory disease of the breast [1]. The time interval between the last childbirth and presentation of the first symptoms ranges from 1to 15 years [4,5]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.