Abstract
Herein is reported the case of a mantle cell lymphoma (MCL) with synchronous double intestinal location. A 74 - year old male presented with mild abdominal pain. CT scan imaging indicated invasion of lateral intestinal cavity by large mass formation. Exploratory laparotomy was performed and two solid extra-mural masses were isolated and excised. Histology revealed non- polypoid double synchronous lymphoma of mantle cell origin, an unusual presentation of the disease.
Highlights
Mantle cell lymphoma (ICD-O code 9673/3) is a subtype in the wide category of B- cell lymphomas [1,2]
The histological derivation is from the “naïve” CD5+ B- cells residing in the primary follicles or in the mantle zones of secondary follicles [4]
Mantle cell lymphoma is an entity of B- cell malignancies, belonging in the non- Hodgkin lymphomas [1,2,6]
Summary
Mantle cell lymphoma (ICD-O code 9673/3) is a subtype in the wide category of B- cell lymphomas [1,2]. At the time of diagnosis most patients have signs of multiple lymphatic involvement, including spleen, red bone marrow, cervical lymph nodes, liver, and gastrointestinal tract, usually under a condition known as “multiple small intestine polyps” [6,7,8]. A large extraluminal mass of approximate dimension 13 cm in diameter was detected at the level of ileum Another smaller mass of 4-5 cm was revealed at 20 cm distance from the first finding, presenting similar macroscopic aspect. The patient’s postoperative course was uncomplicated, with immediate mobilisation and normal intestinal functionality He was discharged from hospital 10 days later in a general good status and after an interval of 22 days he initiated adjuvant chemotherapy (CHOP regiment) administered in a single day every 3 weeks for 6 cycles. A complete physical and imaging evaluation 21 months later revealed complete recovery and no signs of remaining disease
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