Abstract
To evaluate the changes in CCA-IMT and vascular elasticity in healthy subjects in relation to age using radiofrequency data technology, to produce reference values for potential clinical applications. The following variables were measured in 160 subjects using radiofrequency data techniques: CCA-IMT, carotid distensibility (CD), local pulse-wave velocity (PWVβ), and stiffness (β). The subjects were divided into four age groups (30-39, 40-49, 50-59, and 60-69 years), with 20 men and 20 women in each group. The above parameters were compared among the different age groups. CCA-IMT increased significantly with age (p<0.05). CD decreased significantly in the 40-49-years compared with the 30-39-years age group (p<0.05). PWVβ showed a significant increase in the 30-39-, 40-49-, and 50-59-years age groups (p<0.05). β increased significantly in the 50-59- compared with the 40-49-years age group (p<0.05). Compared with the 50-59-years age group, CD, PWVβ, and β showed no significant changes in the 60-69-years age group (p>0.05), with mean values of 329.39±102.06 μm, 7.22±1.91 m/s, and 10.04±4.91, respectively. Ultrasound radiofrequency data technology provides a non-invasive method for quantitatively and accurately assessing increased CCA-IMT and reduced vascular elasticity in healthy subjects in different age groups. The reference values produced in this study will be useful in clinical practice.
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