Abstract

Cancers are one of the deadliest diseases with a costly treatment system in the world at present. In this paper a cost-effective, autonomous system of cancer-cell detection was proposed using several efficient image processing methods to develop an early stage non-Hodgkin type lymphoma which is a type of blood cancer. The system is implemented automatically to detect the traits of cancer in microscopy images of biopsy samples. Recent attempts have previously lacked flexibility in characteristics and the accuracy level is not consistent with the individual cancer type. The framework consisted three stages for detecting cancer on the basis of various detected traits including cell segmentation, quantification, area measurement analysis of cells, a center clump detection using the moment of image, identification of 4-connected components and Moore-Neighbor tracing algorithm. This methodology has been used in several sets of images and Feedback from these test executions has been used to improve the system. Subsequently, the proposed method can be used efficiently for used for autonomous non-hodgking type lymphoma cancer cell detection, which has an accuracy of 93.75%.

Highlights

  • The term cancer is referred to as a barrier to anomalous cell division

  • Even though the process is lengthy and difficult, but knowing more will enable doctors to cure cancer patients more effectively. This motivated us to think about the mechanism of cancer detection and use technology to speed up the process

  • An automatic detection method was introduced by Agaian, S. et al for Acute Myelogenous Leukemia where 80 microscopic image data, collected from the American Haematology Society, were used

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Summary

INTRODUCTION

The term cancer is referred to as a barrier to anomalous cell division. Cancer cells can migrate across blood, lymph systems and tumors to other areas of the body. Even though the process is lengthy and difficult, but knowing more will enable doctors to cure cancer patients more effectively. This motivated us to think about the mechanism of cancer detection and use technology to speed up the process. Leukemia detection with leucocytes classification was performed by Putzu, L. et al [6] using image processing techniques including color conversation, contrast stretching, applying Zack Algorithm for segmentation, removing backgrounds and so on. Total seven types of feature extraction calculation were applied including measurement of roundness, convexity, compactness, elongations, eccentricity, rectangularity, and these were fed SVM classifier where the accuracy was more than 80% deploying on 33 test images

THEORITICAL STUDIES
Douglas-Peucker Algorithm
Moore’s Neighbor Tracing Algorithm
Image Segmentation
Pre-processing
Clump Detection based on Center and Distance Measuring
AND DISCUSSION
Findings
CONCLUSION
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