Abstract

Non-dominant Primary Motor Cortex Repetitive Transcranial Magnetic Stimulation for Moderate to Severe Chronic Pain Caused by Diabetic Neuropathy: Case Series from a Small Crossover Pilot Study

Highlights

  • Repetitive transcranial magnetic stimulation is a relatively new therapeutic technique with an excellent safety profile but mixed results concerning neuropathic pain

  • Patients suffering from chronic pain caused by diabetic neuropathy could benefit from a technique with a safety profile such as that of Repetitive transcranial magnetic stimulation (rTMS) since multiple complications and comorbidities expose them to adverse events related to polypharmacy[4]

  • The intervention consisted of sham and active high frequency rTMS applied to the primary motor cortex corresponding to the non-dominant hand area

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Summary

Introduction

Repetitive transcranial magnetic stimulation (rTMS) is a relatively new therapeutic technique with an excellent safety profile but mixed results concerning neuropathic pain. Methods: Three patients suffering from moderate to severe chronic pain caused by diabetic neuropathy underwent high frequency (10 Hz) rTMS of the primary motor cortex corresponding to the non-dominant hand area. Conclusion: High frequency rTMS of the primary motor cortex corresponding to the non-dominant hand area shows promise in alleviating chronic pain caused by diabetic neuropathy. Repetitive transcranial magnetic stimulation (rTMS) is a relatively new therapeutic and diagnostic technique that uses non-invasive neuromodulation and has an excellent safety profile[1]. Patients suffering from chronic pain caused by diabetic neuropathy could benefit from a technique with a safety profile such as that of rTMS since multiple complications and comorbidities expose them to adverse events related to polypharmacy[4]

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