Abstract
IntroductionDiabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus.Case presentationWe report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes.ConclusionRenal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject.
Highlights
Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus
Case presentation: We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes
In Tunisia, it is turning out to be a major cause of end-stage renal diseases (ESRD), diabetic nephropathy rising at the rate of 16.1% yearly [3,4]
Summary
The incidence and prevalence of diabetes mellitus (DM) are increasing. Tunisia, like most countries of the world, is experiencing an alarming rise in the number of people with diabetes. The prevalence of diabetic nephropathy (DN) is increasing It has become the leading cause of end-stage renal diseases (ESRD) in developed countries. Case presentation We report the case of a 49-year-old Arabic Tunisian man without prior history of diabetes mellitus who presented with rapidly progressive renal failure. Her medical history (page number not for citation purposes). Urine microscopy showed the presence of red blood cells (70000/ml). Our patient did not have a prior diagnosis of DM or other clinical or biological manifestations of other systemic disease which could be responsible for the nephropathy These findings led to the diagnosis of rapidly progressive glomerulonephritis and realization of renal biopsy.
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