Abstract

Current literature details an array of contradictory results regarding the effect of radiofrequency electromagnetic radiation (RF-EMR) on health, both in humans and in animal models. The present study was designed to ascertain the conflicting data published regarding the possible impact of cellular exposure (radiation) on male and female mice as far as spatial memory, anxiety, and general well-being is concerned. To increase the likelihood of identifying possible “subtle” effects, we chose to test it in already cognitively impaired (following mild traumatic brain injury; mTBI) mice. Exposure to cellular radiation by itself had no significant impact on anxiety levels or spatial/visual memory in mice. When examining the dual impact of mTBI and cellular radiation on anxiety, no differences were found in the anxiety-like behavior as seen at the elevated plus maze (EPM). When exposed to both mTBI and cellular radiation, our results show improvement of visual memory impairment in both female and male mice, but worsening of the spatial memory of female mice. These results do not allow for a decisive conclusion regarding the possible hazards of cellular radiation on brain function in mice, and the mTBI did not facilitate identification of subtle effects by augmenting them.

Highlights

  • Cell phone electromagnetic radiationIt is estimated that as of the end of 2020, about 50% of the world’s population relies on cell phones for communication.[1]

  • The public health concern regarding the potential risk of chronic exposure to the low levels of radiofrequency and microwave (RF/MW) or electromagnetic radiation (EMR) that is emitted by the phone antenna, derives from the use of the device in close proximity to the user’s head.[7]

  • All groups spent approximately equal time in the open arm of the maze and could not be differentiated from one another, indicating that cellular radiation and mTBI does not increase anxiety-like behavior (Fig. 2 A,B)

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Summary

Introduction

Cell phone electromagnetic radiationIt is estimated that as of the end of 2020, about 50% of the world’s population relies on cell phones for communication.[1]. The public health concern regarding the potential risk of chronic exposure to the low levels of radiofrequency and microwave (RF/MW) or electromagnetic radiation (EMR) that is emitted by the phone antenna, derives from the use of the device in close proximity to the user’s head.[7]. This Null Hypothesis article is published as part of a collaborative effort between Cohen Veterans Bioscience, the Center for Biomedical Research Transparency (CMBRT), and Mary Ann Liebert, Inc., publishers to promote open science through publication of high-quality studies, including those with negative, inconclusive, and confirmatory results. Cohen Veterans Bioscience, CBMRT, and the Publisher disclaim any liability to any party for the accuracy, completeness, efficacy, or availability of the material contained in this publication

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