Abstract
This article comments on:Calvo-Begueria L, Rubio MC, Martinez JI, Perez-Rontome C, Delgado MJ, Bedmar EJ, Becana M. 2018. Redefining nitric oxide production in legume nodules through complementary insights from electron paramagnetic resonance spectroscopy and specific fluorescent probes . Journal of Experimental Botany 69, 3703–3714.
Highlights
Nitric oxide (NO) is an important redox molecule fulfilling a wide variety of signalling functions
One of its most important modes of action is protein S-nitrosation, the covalent attachment of NO to the thiol group of protein cysteine residues.Tyrosine nitration refers to the addition of a nitro group to susceptible tyrosine residues in the ortho position to the hydroxyl group yielding 3-nitrotyrosine
Investigation of NO production and NO signalling is challenging because many available methods suffer from a lack of specificity and/or sensitivity, or are just unsuitable for the detection of NO in vivo.in some cases, the production might be restricted to a few cells, such as guard cells or pollen (Corpas et al, 2004; Prado et al, 2004; Neil et al, 2008)
Summary
Nitric oxide (NO) is involved in regulation of plant growth and development, as well as the response to biotic and abiotic stressors. Nitric oxide (NO) is an important redox molecule fulfilling a wide variety of signalling functions. These cover growth and development, as well as stress responses, in humans, animals, plants, fungi and bacteria (Besson-Bard et al, 2008; Sudhamsu and Crane, 2009; Murad, 2011; Arasimowicz-Jelonek and Floryszak-Wieczorek, 2016; Byung-Wook et al, 2016; Canovas et al, 2016). NO can be produced by oxidative and reductive pathways (Moreau et al, 2010;Yu et al, 2014) and is sensed within the cell through redox modification of proteins, such as cysteine nitrosation, tyrosine nitration and metal nitrosylation (Astier et al, 2012; Astier and Lindermayr, 2012; Mata-Perez et al, 2016). In a direct metal nitrosylation reaction, NO (Lewis base) binds to the transition metal (Lewis acid) of metalloproteins yielding a metal–nitrosyl complex
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
