Abstract
We developed a Co single-atom catalyst (Co-SAC) containing atomically dispersed Co atoms that exhibited intrinsic oxidase-like activity for sustainable antibacterial activity and wound healing. Benefiting from the good photothermal effect, the Co-SAC nanozyme presented enhanced oxidase-like activity and antibacterial efficiency via the generation of heat and superoxide radicals under near-infrared II laser light (1064 nm). In virtue of the outstanding oxidase-like activity, the Co-SAC nanozyme could eliminate pathogenic bacteria and disrupt the formation of biofilm without any additional H2O2. The accelerated wound healing was achieved in an in vivo wound model infected by S. aureus without significant side effects, which showed promising applications in antibacterials and wound healing. Such a strategy would possibly open a new window for translational medicine of Co-SAC nanozyme.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
