Abstract
Nicardipine: Concise Review on Analytical Techniques
Highlights
IntroductionCopyright © All rights are reserved by Pritam Jain S
Copyright © All rights are reserved by Pritam Jain S.Arch Nano Op Acc JVolume 1 - Issue 5Copyrights @ Pritam Jain S, et al.Nicardipine is chemically identified as 1, 4-Dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-3, 5-pyridinedicarboxylic acid methyl 2-[methyl-(phenylmethyl) amino]ethyl ester (Figure 1)
The melting point of NCD in the range of 136-138 °C (277-280 °F) [2].It is a calcium channel antagonist class of dihydropyridine. It is used for the treatment of angina pectoris and used in the managing of hypertension [3]
Summary
Copyright © All rights are reserved by Pritam Jain S. Copyrights @ Pritam Jain S, et al. Nicardipine is chemically identified as 1, 4-Dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-3, 5-pyridinedicarboxylic acid methyl 2-[methyl-(phenylmethyl) amino]ethyl ester (Figure 1). The molecular weight of NCD is 479.52 [1]. The melting point of NCD in the range of 136-138 °C (277-280 °F) [2].It is a calcium channel antagonist class of dihydropyridine. It is used for the treatment of angina pectoris and used in the managing of hypertension [3]. Most CCBs, including amlodipine, felodipine, isradipine, nicardipine, and nifedipine, belong to the dihydropyridine class [4]. The dihydropyridine have little direct effect on cardiac tissue at typical therapeutic levels; yet, they can evoke reflex tachycardia [5]
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