Abstract
Influenza is an ongoing public health threat. The accurate diagnosis of influenza is a significant challenge to health care providers, clinical laboratories, and public health officials because the diagnosis of influenza is not easily made on the basis of the clinical presentation alone. Identification of influenza infection as soon as possible after onset of symptoms improves patient management and infection control. Traditional rapid influenza diagnostic tests (RIDTs), such as lateral flow immunoassays, are simple to use and provide results in less than 30 minutes at the point of care. These RIDTs are less accurate than more complex, but more definitive, tests performed in centralized laboratories. A new era of influenza diagnostics is emerging in which more accurate and objective next-generation RIDTs, based on fluorescent immunoassay technology, are available. We review recent studies on the performance of this technology and enumerate its advantages compared with traditional RIDTs. This technology offers an opportunity for significant improvement in how influenza is managed.
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