Abstract

Acne has long been recognized as a widespread skin condition, and its prevalence is currently increasing. One of the top 10 epidemics in the world right now, it has a serious psychological toll on its victims. Four interconnected processes, including inflammation, increased sebum production, follicular infundibular hyperkeratosis, and Chlamydia acne growth, make up the disease's complicated pathophysiology. Antibiotics that target P. acnes have been a successful and popular way to treat acne for the past 40 years, even though the pathophysiology of acne is not entirely understood. The emergence of antibiotic resistance, however, is a persistent issue with a variety of negative consequences. Isotretinoin and antiandrogen therapy are frequent therapies for certain of them. This article summarizes the effectiveness and safety of oral antibiotics for acne treatment in recent years as well as some other recent treatment research, operating under the premise that the current domestic and international clinical trials of acne vulgaris are insufficient. The goal is to raise awareness of acne vulgaris.

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