Abstract

Osteonecrosis of the jaw (ONJ) is a complication associated with the use of bisphosphonates (BPs) in patients with multiple mieloma (MM). It is known that the previous dental procedures can precipitate the development of ONJ, but other risk factors remain unexplored. Recently, has been described the implication of other drugs in ONJ, mainly antiangiogenic treatments, but their study in the context of MM has not been performed. Objective To study the characteristics and risk factors currently implicated in the development of ONJ in patients with symptomatic MM in 13 Spanish hospitals in the last 10 years.

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