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New equation for a spin 1/2 particle with three additional characteristics in presence of electromagnetic and gravitational fields

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Within the general Gel’fand–Yaglom method, starting from the extended 28-component representation of the Lorentz group, we construct a new relativistic P-invariant generalized equation for a spin-1/2 particle possessing three characteristics in addition to the electric charge. The model is first developed for a free particle, where the corresponding system of spinor equations is derived and then transformed into spin-tensor form. In this form, we incorporate the interaction with external electromagnetic fields. By eliminating the accessory variables of the complete wave function, we obtain a minimal four-component Dirac-like equation that contains three new interaction terms, interpreted as arising from the additional electromagnetic characteristics of the particle. This approach is further extended to a Riemann space–time background within the conventional tetrad formalism, leading to additional geometrical interaction terms involving the Ricci scalar R(x), the Ricci tensor Rαβ, and the Riemann curvature tensor Rαβρσ(x).

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Electromagnetic fields (EMFs) are ever-present, and so is the need to better understand their influence on human health and biological matter in general. The interaction between a molecular system and external EMF can alter the structure, and dynamical behaviour, and, hence, biological function of proteins with uncertain health consequences. This urges a detailed investigation of EMF-induced effects on basic protein biophysics. Here, we used all-atom non-equilibrium molecular dynamics simulations to understand and quantify the response mechanisms of the amyloidogenic apoC-II(60-70) peptides to non-ionising radiation by modelling their behaviour under external electromagnetic and electric fields of different strengths. Our simulations show high strength fields (>0.04 V/nm) cause structural changes in apoC-II(60-70) due to the peptide dipole alignment along the applied field direction, which disrupts the inherent β-hairpin conformation known to be the intermediate state for fibril formation. The intermediate field-strength range (0.04-0.004 V/nm) causes a significant acceleration in peptide dynamics, which leads to the increased population of structures with fibril-inhibiting characteristics, such as the separated N- and C-termini and colocation of the aromatic residues at the same peptide face. In contrast, lower field strengths (<0.004 V/nm) promote the formation of the amyloid-prone hairpin structures relative to the ambient conditions. These findings suggest that intermediate-strength electromagnetic fields could be considered for designing alternative treatments of amyloid diseases, while the very high and low field strengths could be employed for engineering well-ordered fibrillar aggregates for non-medicinal applications.

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Nonequilibrium molecular-dynamics (MD) simulations have been performed for the growth and dissolution of a spherical methane hydrate crystallite, surrounded by a saturated water-methane liquid phase, in both the absence and presence of external electromagnetic (e/m) fields in the microwave to far infrared range (5-7500 GHz) at root-mean square (rms) electric field intensities of up to 0.2 V/A. A rigid/polarizable potential was used to model water and a rigid/nonpolarizable model was utilized for methane. In the absence of a field, it was found that the average growth rate of the crystallite was approximately 0.32 water and 0.045 methane molecules per picosecond, evaluated over a 500 ps NPT simulation for three different initial geometries. Upon the application of an e/m field, it was found that no significant deviations from the zero-field crystal growth patterns were observed for rms electric field intensities of less than about 0.1 V/A, regardless of the field frequency. At, and above, this "threshold" intensity, it was found that dissolution took place. The mobility of the molecules in the system was enhanced by the e/m field, to the greatest extent for frequencies of 50-100 GHz. Furthermore, it was observed that there was a systematic frequency variation in the pattern of dipole alignment with the external field and this led to marked differences in the rate of dissolution.

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Calculation of the electric field and potential inside a wire structured object in an external pulse electromagnetic field of a lightning discharge is presented. The conductive structure is solved as a receiving antenna using program SPAN for an arbitrary antenna configuration, consisting of lineic cylindrical segments, in external electromagnetic field. One simple approximation for the external pulse field is used, the parameters of which are calculated for a standard pulse function. The fast Fourier transform (FFT) is performed on this function and antenna response in the time domain is obtained using the inverse fast Fourier transform (IFFT) to the results of the program SPAN in the frequency domain. The results for the electric field and for the potential, as the consequences of induced currents, are presented in the form of graphics.

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