Abstract

We created a new imaging technique that detects and emphasizes turbulence, which is a characteristic of blood flow in hepatocellular carcinoma. We devised two indices that determine a characteristic tumor flow, the bi-directional and low-peak indices. In the phantom study, both indices of turbulence caused by a stenosis were much higher. In the clinical study, both indices were significantly higher in tumors than in the portal vein or hepatic vein. A turbulent blood flow was detected in 77% of tumors, whereas such detection seldom occurred in the portal or hepatic vein. This technique has the potential to distinguish turbulence in hepatocellular carcinoma.

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