Abstract
A new and efficient method for the construction of 2,3,4-trisubstituted 2H-pyrrolo[3,4-c]quinoline derivatives was developed. Starting from easily accessible 2-azidobenzaldehyde, nitromethane, 1,3-dicarbonyl compounds, and various amines gave the multicomponent reaction (MCR) products, 1-substituted 3-acyl-4-(2-azidophenyl)-2-methyl-1H-pyrroles, that underwent Staudinger/aza-Wittig cyclization of in the presence of triphenylphosphine to give the final products.
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