Abstract

AimTo study the 9, 19-cycloartane triterpenes from the roots of Cimicifuga foetida. MethodChromatographic separations by silica gel, C18 reversed phase silica gel, and high-performance liquid chromatography (HPLC) were used. All of the structures were elucidated on the basis of spectroscopic analysis and chemical methods. ResultsFive 9, 19-cycloartane triterpenes, (3β, 12β, 15α, 24R)-12, 2′-diacetoxy-24, 25-epoxy-15-hydroxy-16, 23-dione-3-O-α-L-arabinopyranoside (1), actein (2), 23-epi-26-deoxyactein (3), asiaticoside B (4), and 12β-hydroxycimigenol (5) were isolated from the roots of Cimicifuga foetida. ConclusionCompound 1 is a new triterpene with two acetoxy groups at C-2′ and C-12.

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