Abstract
LITTLE is known about the mechanism of the spreading of snake venoms through the body of the victim. Duran-Reynals1 postulated a “spreading factor” in snake venoms, which was identified by Chain and Duthie2 as hyaluronidase. While the spreading of elapide venoms may be correlated to some extent to their hyaluronidase content, very little3 or no hyaluronidase was found in viperide venoms.
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