Abstract
Sera from 71 adult channel catfish (Ictalurus punctatus), with a history of channel catfish virus (CCV) association, were assayed for CCV neutralization activity. Sixty-seven serum samples had positive CCV neutralization indices. Sera from 10 fish with no known history of CCV exposure, showed no evidence of virus neutralization activity. Viable CCV was not isolated from 232 organs or excretory products of studied fish. Serum from channel catfish experimentally immunized with viable CCV reached peak neutralization indices 60 days after virus injection. Detection of CCV serum neutralization activity can afford a possible method of identifying channel catfish populations with a previous exposure to CCV.
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