Abstract
BackgroundThe coronavirus disease due to SARS COVID-2 emerged from Wuhan city in China in December 2019 and rapidly spread to more than 200 countries all over the world as a global health pandemic. Its primary presentation is respiratory and cardiac. However, some neurological manifestations are also reported. We tried to explore the reported neurological manifestations in a group of non-hospitalized mild and moderate COVID-19 patients. We contacted 107 patients via phone calls and e-mail messages, within 10 days of clinical presentation. The collected data regarded the neurological and non-neurological symptoms of the disease using a questionnaire that collected medical information of each patient.ResultsIt is found that 100% of patients have been reported with at least one neurological symptom during the first 10 days of COVID-19 presentation. The most common were headache which recorded 72% of the total. Then anosmia–dysgeusia which reached 52%, then myalgia with 44%, fatigue with 33% and dizziness with 32%. While the less common was numbness, migraine, loss of concentration, and seizures.ConclusionThere are many neurological manifestations found to be very common in COVID-19 patients even in mild cases, which when added to the increasing reports of serious cases of Guillain–Barre syndrome, acute necrotizing encephalopathy, myelitis, stroke, and encephalitis in COVID-19 patients support CNS invasion of the virus and assures the importance of neurological assessment of COVID-19 patients both in the acute phase of infection and after recovery for potential neurological sequelae.
Highlights
The coronavirus disease due to Severe acute respiratory syndrome (SARS) COVID-2 emerged from Wuhan city in China in December 2019 and rapidly spread to more than 200 countries all over the world as a global health pandemic
We collected data of a group of non-hospitalized mild-to-moderate cases of COVID19 through phone calls, as they were isolated for diagnosis of COVID-19
One hundred and seven patients participated in the study
Summary
The coronavirus disease due to SARS COVID-2 emerged from Wuhan city in China in December 2019 and rapidly spread to more than 200 countries all over the world as a global health pandemic. We tried to explore the reported neurological manifestations in a group of non-hospitalized mild and moderate COVID-19 patients. Most patients infected by the virus have presented with a mild clinical course, starting with fever and dry cough, progressing to mild or moderate respiratory disease. The previous reports on neurological complications of COVID-19 are restricted to few cases or case series of hospitalized patients presenting with more severe. How common are neurological symptoms in mild non-hospitalized cases of COVID-19, and whether it affects the central or the peripheral nervous system, and are they correlated with symptoms of other affected organs? To answer these questions, we collected data of a group of non-hospitalized mild-to-moderate cases of COVID19 through phone calls, as they were isolated for diagnosis of COVID-19
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