Abstract
Belongs to the primitive neurectodermal tumours (PNET): highly malignant embryonal tumours of the CNS with predominant neuronal differentiation. Several variants medulloblastoma are recognized in the OMS classification: Classic medulloblastoma composed of densely jacked round-cells with round to oval hyperchromatic nuclei. Desmoplastic medulloblastoma represents a variant with abundant reticulin and collagen. Large cell medulloblastoma is a rare variant composed of cells with large round nuclei.
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