Abstract

Objective To compare the effect of nerve block in the level of transversus abdominis muscle combined with dexmedetomidine vs.general anesthesia in the catheterization of peritoneal dialysis in patients with renal failure. Methods Eighty patients with renal failure were chosen and divided randomly into two groups.One group received nerve block in the level of transverses abdomins muscle(D group),and the other received general anesthesia(G group).The changes in mean arterial pressure(MAP), heart rate (HR)and the incidence of adverse reactions were recorded during the perioperative period. Results There was no significant difference in general conditions and vital signs between the two groups.Five min after the operation started, the MAP in G group(118. 50±19. 59) mm Hg(1 mm Hg= 0. 133 kPa) was higher than that in D group(109. 78±12. 16)mm Hg; The heart rate in G group(82. 03±13. 66)bpm was quicker than that in D group(60. 51±12. 11)bpm.Furthermore, the incidence of adverse reactions in G group (8 cases)in perioperative period was higher than that in D group(one case).The incidence of postoperative complications in G group(14)was higher than that in D group(two). Conclusion Nerve block in the level of transversus abdominis muscle combined with dexmedetomidine is effective and safe when used in catheterization of peritoneal dialysis in patients with renal failure.It may be a better anaesthetic method in patients with renal failure in future. Key words: Peritoneal dialysis; Nerve block in the level of transversus abdominis muscle; General anesthesia

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