Abstract
A scientific controversy that exploded into public view about five years ago, and has been quietly simmering since, has erupted again. Last week, a British research team published findings in Nature [ 366 , 525 (1993)] that the journal says decisively contradict amazing results published in 1988 in Nature [ 333 , 816] by an international team led by Jacques Benveniste, a respected pharmacologist. Benveniste is research director at a unit of the French National Institute of Health & Medical Research (INSERM) located at the University of Paris-South in Clamart, a Paris suburb. The gist of Benveniste's paper is that an aqueous solution of an antibody retains its ability to evoke a biological response even when so diluted that not a single antibody molecule can be expected to remain. Furthermore, the paper says that for the effects to be observed, the dilutions need to be accompanied by vigorous shaking. Benveniste's group claimed that the shaking causes an imprint of ...
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