Abstract

Two new rhamnosides, 18-O-α-l-rhamnopyranosylabietic acid (1) and (E)-3,5-dimethoxystilben-4′-O-α-l-rhamnopyranoside (2), five known glucosides (3–7) along with three others were isolated from Cynanchum atratum roots. The structures of new compounds were elucidated by physical data analyses such as NMR, UV, IR, HR-ESI-MS, as well as acid hydrolysis. All of them were assessed for their antioxidant activities through 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radical ion (ABTS•+), 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH•) and 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide radical (PTIO•) assay, with l-ascorbic acid used as the positive control. As a result, compounds 3–5 exhibited obvious antioxidant activities. These bioactive components could be promising antioxidants.

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