Nasal polyp : A clinico histological study

Abstract

A total of 113 cases of nasal polypi from almost all age groups, having almost equal sex incidence, were subjected to clinico histological study, in an attempt to subgroup nasal polyp on etiological basis. History of allergic manifestations could not be elicited in most of the cases (65.5%). Ulceration with ciliated columnar and transitional epithelium were seen in good number of cases (93.8%). Infiltration of stroma by lymphocytes, plasma cells, macrophages, eosiniphils and mast cells Were plenty to moderate in number with almost equal frequency, although 22.1% of cases showed poor number of eosinophils and mast cells, while polymorphs in poor number were detected in 70.8% of cases. Stroma was severely or moderately oedematous in most of the cases. Presence of amyloid like material was noted in 80.6% of cases. Atypical mesenchymal cells were seen in plenty to moderate number in 36 3% of cases. Seventy six cases could be followed up, of whom 11 cases showed recurrence within 6 months. Histological picture in these cases didnot reveal mesenchymal cell atypicality as a factor for recurrence. The present study also could not catagorise the nasal polypi as allergic or nonallergic on the basis of gland histology and character of cellular infiltrate.