Abstract
The adhesive external nasal dilator strip (ENDS) is widely advocated for prevention of snoring and promotion of nasal breathing during exercise. In the present study, the effects of the ENDS on nasal airflow resistance (Rn) in normal subjects were examined and factors determining individual responses to the ENDS explored. Using posterior rhinomanometry, 20 healthy Caucasian adults (10 males, 10 females; age: 18-56 yrs) were studied during quiet tidal breathing and voluntary hyperpnoea with (ENDS) and without (control) ENDS and with a placebo strip (placebo) before and after application of a topical nasal decongestant (oxymetazoline hydrochloride). During tidal breathing, only nine subjects showed a significantly (p<0.05) decreased inspiratory and/or expiratory Rn with the ENDS ("responders"). During the control, inspiratory Rn (at 0.4 L x s(-1)) was higher in "responders" than "nonresponders" (3.28+/-0.16 versus 2.60+/-0.08 cmH2O x L(-1) x s; p=0.04). The effects of nasal decongestant and the ENDS were additive. During voluntary hyperpnoea, inspiratory Rn (at 1.0 L x s(-1)) and the hysteresis of the inspiratory transnasal pressure/flow curve were decreased with the ENDS in most subjects. It is concluded that the external nasal dilator strip influences nasal airflow dynamics by both dilation of the nasal valve and stabilization of the lateral nasal vestibule walls and may be more effective in subjects with a high resting nasal airflow resistance.
Highlights
Using posterior rhinomanometry, 20 healthy Caucasian adults (10 males, 10 females; age: 18±56 yrs) were studied during quiet tidal breathing and voluntary hyperpnoea with (ENDS) and without external nasal dilator strip (ENDS) and with a placebo strip before and after application of a topical nasal decongestant
Consisting of two parallel flat polyester springs enclosed by an adhesive tape covering, when properly positioned and fastened to the skin over the dorsum of the nose, this device exerts a truss-like action, lifting the skin over the lateral nasal vestibule walls
Representative transnasal pressure/flow plots obtained in one subject during control and administration of placebo and the ENDS are shown in figure 1
Summary
20 healthy Caucasian adults (10 males, 10 females; age: 18±56 yrs) were studied during quiet tidal breathing and voluntary hyperpnoea with (ENDS) and without (control) ENDS and with a placebo strip (placebo) before and after application of a topical nasal decongestant (oxymetazoline hydrochloride). Consisting of two parallel flat polyester springs enclosed by an adhesive tape covering, when properly positioned and fastened to the skin over the dorsum of the nose, this device exerts a truss-like action (resulting from the recoil forces created by bending the polyester springs), lifting the skin (via the adhesive connection) over the lateral nasal vestibule walls. Transmission of this force to the internal nasal walls leads to mechanical dilation of the nasal airway [1]
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