Nanosuspensions for improved Cancer Therapy: A Comprehensive Review

Abstract

Cancer continues to be a major cause of sickness and death in the world's health. Conventional cancer treatments, such radiation and chemotherapy, frequently have drawbacks like poor solubility, limited absorption, and non-specific targeting, which can result in systemic toxicity and decreased efficacy. To get over these restrictions and improve cancer therapy, nanosuspensions—submicron colloidal dispersions of drug particles stabilized by polymers and/or surfactants—have become a viable new approach. This review provides a comprehensive overview of nanosuspensions, including their preparation methods, characterization techniques, and therapeutic applications in cancer treatment. The potential advantages of nanosuspensions over conventional formulations, such as improved solubility, enhanced bioavailability, and tumor-targeted delivery, are discussed in detail. The potential advantages of nanosuspensions over conventional formulations, such as improved solubility, enhanced bioavailability, and tumor-targeted delivery, are discussed in detail. Recent advances in nanosuspension technology, including the development of stimuli-responsive and multifunctional nanosuspensions, are also highlighted. Recent advances in nanosuspension technology, including the development of stimuli-responsive and multifunctional nanosuspensions, are also highlighted. Finally, the challenges and future directions of nanosuspensions in cancer therapy are explored.