Abstract
Background Patients' clinical antibiotic treatment of deep II degree burns usually fails to achieve the ideal effect; in order to avoid the late result in pigmentation, scarring, and even limb dysfunction, it also needs to deal effectively with burn wounds. Aim The purpose of this study is to evaluate nanosilver dressing in treating deep II degree burn wound infection in patients with clinical studies. Materials and Methods 106 burn patients were classified into the Sulfadiazine Silver Cream (SSC) group (n = 53) and the Nanosilver Burn Dressing (NSBD) group (n = 53). Both of them received basic wound treatment, and wound healing time and pigmentation fading away time of all patients were recorded. And the wound healing rate of the patients was calculated. Serum levels of tumor necrosis factor alpha (TNF-α) and interleukin-1beta (IL-1β) were detected pre- and posttreatment. Results After basic treatment for all patients, Sulfadiazine Silver Cream was used in the SSC group, and Nanosilver Burn Dressing was used in the NSBD group. It was observed that after treatment, compared with the SSC group, there was significant efficiency; wound healing rate, healing time, and pigmentation fading away time were shortened in the NSBD group, and IL-1β levels were decreased, and the positive rate of bacterial culture was decreased (all P < 0.05). Conclusion Nanosilver Burn Dressing in treating deep II degree burns can effectively reduce the wound infection and promote wound healing. The curative effect was distinct, which was worthy of popularization and application.
Highlights
Burn is a kind of tissue damage caused by fire, electricity, high temperature, and strongly hot objects or chemicals
Deep II degree burns belong to severe burns and have a wide range from burns, the wound healing is slow, and the burn injury is to the dermis, which can lead
The results of this study indicated that in comparison with the patients who used Sulfadiazine Silver Cream for dressing change, the total significant effectivity and wound healing rate of the patients who used Nanosilver Burn Dressing were significantly higher, and the positive rate of wound secretion was significantly reduced after bacterial culture
Summary
Burn is a kind of tissue damage caused by fire, electricity, high temperature, and strongly hot objects or chemicals. Sulfadiazine Silver Cream is a commonly used sulfadiazine antimicrobial agent It can achieve good antimicrobial effect, its irritation is relatively large and it is easy to cause scarred burn wounds in patients [5]. 106 burn patients were classified into the Sulfadiazine Silver Cream (SSC) group (n = 53) and the Nanosilver Burn Dressing (NSBD) group (n = 53). Both of them received basic wound treatment, and wound healing time and pigmentation fading away time of all patients were recorded. After basic treatment for all patients, Sulfadiazine Silver Cream was used in the SSC group, and Nanosilver Burn Dressing was used in the NSBD group. The curative effect was distinct, which was worthy of popularization and application
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