Nanoparticles in Growth Factor Therapy: A Promising Approach for Tissue Regeneration

Abstract

Nanoparticles (NP) are being explored as a promising approach for growth factor therapy in tissue regeneration. Growth factors play a critical role in tissue regeneration by stimulating cell growth, proliferation, and differentiation. However, the use of conventional growth factor therapy is limited by their short half-lives, rapid clearance from the body, and difficulties in delivering them to the target site. To overcome these challenges, nanoparticles have been used to encapsulate growth factors, providing a sustained and localized delivery system. The aim of this article focuses on the most recent advancements in Growth Factor Therapy (GFT), where tissue generation (TR) and cell therapy depend heavily on iron oxide nanoparticles (IONPs). Additionally, the presence of magnetic fields can use mechanotransduction to drive cell differentiation into a particular cell type or to specifically route IONP-labeled cells to the site of action. Further research is needed to fully understand the safety and efficacy of using nanoparticles in therapeutic applications, but their potential to revolutionize tissue regeneration and provide better treatment options for patients suffering from various diseases and injuries is significant