N-acetylcysteine: Impact on Psychiatric Disorders

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Abstract N-acetylcysteine (NAC) is becoming more and more popular medication in the management of mental health conditions. NAC antiinflammatory, antioxidant and glutamate transmission properties, currently being explored for the therapeutic intervention of neurological conditions, e.g. anxiety, depressive disorders, post-traumatic stress disorder, obsessive-compulsive disorders, bipolar disorders and schizophrenia. Clinical studies for many psychiatric diseases have yielded contradictory findings, despite the fact that there is a wealth of preliminary data and intellectual support for the application of NAC in the treatments of many of these illnesses. The most of the research studies have proven insufficient and too briefly explored. More research are required to established NAC efficacy, appropriate indication and adverse drug reactions.