Abstract
A case of lentigo maligna melanoma of the left cheek skin is presented. The patient was 80-year-old woman. Grossly, 10×10mm relatively distinct black nodule and 20×15mm vague brownish macule surrounded the nodule were observed. At scanning magnification, the tumor seemed to be symmetrical and well circumscribed. These finding made us to suspect this tumor as Spitz's nevus. However, the atypical melanocytes proliferated at the junction and infiltrated to the subcutaneous tissue. Furthermore, melanin production was prominent and distributed irregularly in the tumor. At high magnification, mitoses of the atypical melanocytes were numerous even at the deep lesion and atypical ones were found. At the lentigo maligna lesion, atypical melanocytes proliferation were found at the junction.It is important to consider in many aspects when malignant melanoma and Spitz's nevus are to be differentiaed.
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