レーザー血流計による術中心筋組織血流測定法の確立と臨床応用

Abstract

Recently, the technical advance of laser medicine gives us a chance to measure the myocardial blood flow.We experimentally established how to measure the myocardial blood flow using a laser flowmeter(He-Ne laser, wave length 632.8nm) and a small myocardial probe, and applied to the cases of coronary artery bypass grafting (CABG).The probe was positioned between the heart and the elastic mesh bandage (“Presnet”), and fixed on the cardiac surface. The right and left ventricular myocardial blood flow in 14 cases of CABG were counted at pre- and post-bypass grafting.The myocardial blood flow at the anterior wall of right ventricle which had no relation to bypass grafting did not change. The flow of noninfarcted bypassed region significantly(p 0.01) increased from the preoperative value of 78±12 ml/min/100gr to 87±12 ml/min/100gr after the bypass grafting.In conclusion, the noninvasive measurement of myocardial blood flow is obtained by using the laser flowmeter and the specially producted myocardial probe. The coronary artery bypass grafting increases the myocardial blood flow at the noninfarcted ischemic area.