Abstract
Nerve sheath myxoma is a benign tumor originating from the endoneurium. This tumor rarely occurs in the skin, and nerve sheath myxoma involving the oral cavity is extremely rare. Only 19 cases have been reported to date. This report describes a case of nerve sheath myxoma of the buccal softtissues. A 53-year-old man presented with a painless nodule on the right side of the buccal mucosa. The nodule increased gradually over the course of 2 years. At presentation in 2005, the tumor measured 40×20×20mm. Weperformed a biopsy under local anesthesia. Histopathological examination revealed multinodules under the mucosal epithelium. The tumor consisted of spindle cells with a myxoid background that stained with alcian blue.Immunohistochemically, the tumor cells were stained with S-100 protein. These results suggested that the tumor was a nerve sheath myxoma. Therefore, surgical removal of the tumor was performed under general anesthesia. There has been no evidence of recurrence as of 1 year postoperatively.
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