勤労者の血液性状に関する検討

Abstract

In order to establish the normal regions of several hematological measurements in healthy workers, specific gravity of whole blood, red cell count, white cell count, hemoglobin content, hematocrit value and red cell sedimentation rate were examined on 4967 healthy men and 4980 healthy women working in an electronic company in the fall of 1967. 1) Frequency distributions of specific gravity of whole blood, red cell count, hemoglobin content and hematocrit value were found to be close to normal, while these of the logarithmic values of white cell count and red cell sedimentation rate were found to be close to normal in both men and women, although many of the distributions were slightly asymmetric. It was also noticed that the type of the distribution of red cell sedimentation rate found in men was slightly different from that in women. Means and standard deviations of the hematological measurements were calculated by age and by sex (Tab. 2). The age and sex differences of the mean were statistically significant in most of them (Tab. 3), though the value of difference of the mean, relative to the value of the means, by age was small in all hematological measurements. Based on the above findings about the distribution of the hematological measurements, criterions of screening for mass blood examination of workers was proposed (Tab. 9). 2) Means of specific gravities of whole blood, red cell counts, white cell counts, hemoglobin contents and hematocrit values found in this investigation were slightly lower than the so-called normal values hitherto reported. These lower means are supposedly caused by the use of cubital venous blood as blood specimen and by the use of new test method blood and apparatus such as an automatic cell counter and cyanmetohemoglobin. 3) Relatively large positive correlation coefficients were found between four blood measurements-specific gravities of whole blood, red cell counts, hemoglobin contents, hematocrit values-in both men and women. Moreover, the factor pattern for eight variables concerning hematological measurements and body size obtained by principal component analysis and varimax rotation showed in all age and sex groups that about 80% of total communality was to be attributed to four common factors and that all coefficients of the first factor for the above four hematological measurements were large. So, it will be reasonable to presume that any one of the above four hematological measurements can be representative of all the other three hematological measurements to certain extent, although of course each measurement, specific gravity of whole blood, red cell count, hemoglobin content and hematocrit value, has the hematological meaning in its own right.