Abstract

Subcutaneous leiomyosarcoma is a malignant neoplasm that arises from smooth muscle of blood vessels. This tumor usually occur in the extremities and very rarely arises in the head and neck region.We report a case of subcutaneous leiomyosarcoma of the cheek. A 31-year-old woman noticed a swelling of the left cheek in November 1990. Excisional biopsy was carried out at the Department of Dermatology, Tokyo Women's Medical University in November 1990, and leiomyosarcoma was diagnosed. As we were requested to do a wide excision, we performed an additional excision with D-P flap reconstruction in December 1990. There has been no local recurrence or metastasis as of 9 years after operation. In addition to these clinical findings, we discuss histopathological findings of immunohistochemical studies with vimentin, desmin, SMA, EMA, and S-100 antibody and review the literature.

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