Abstract
The purpose of this study was to diagnose the acute stroke by diffusion weighted imaging (DWI) and perfusion image (PI) using echo planar imaging (EPI).Ten cases of acute stroke within 12 hours after onset were imaged with FLAIR, DWI and PI. All imaging was performed using a 1.5 T Signa Horizon MRI scanner (GE-YMS). The imaging parameters of the DWI were employed in four times, namely b=250, 500, 750, 1000 sec/. PI was performed with single shot gradient echo type echo-planar technique during the injection of 0.2 mmol per kilogram of body weight gadopentate dimeglumine, TR/TE=333 ms/55 ms, matrix=128×1 NEX, thickness 5 mm, FOV 24 cm. Apparent diffusion coefficient (ADC) map, relative cerebral blood volume (rCBV) map, and relative mean transit time (rMTT) map were reconstructed by workstation. Measurement of ADC, MTT ratio and CBV ratio in ischemic core and peripheral region were evaluated respectively and compared with follow up imaging in over 1 month after onset.(1) ADC value were reduced to 45.2% and 78.2% in the ischemic core and penumbra respectively. (2) rCBV ratio and rMTT ratio were 32% and 148% in the ischemic core, 73% and 167% in the peripheral region, respectively. (3) Perfusion map can be classified into 4 types according to the grade of ischemia.ADC and perfusion map can demonstrate the grade of ischemia in acute stage.
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