Abstract

Malignant melanomas or lymphoma of the skin are malignant tumors of the skin and/or the mucous membranes whose uterine metastases are rare. The secondary uterine localizations, although rare, must be evoked in front of a pelvic tumoral syndrome, or diffuse metastases and a personal past history of melanoma, even after a long time of remission. In our observation, the evolution of the tumor in the pelvis extended to the muscular structures of the uterus and the sigmoid colon of a 72 year old patient, what made it an exceptional case. The diagnosis of these secondary localizations is a diagnosis of elimination, almost always post-operative, made on the histopathological and immunocytochemical study of the surgical specimen, supported by cytogenetics, even molecular biology. The treatment is based on chemotherapy.

Highlights

  • The evolution of the tumor in the pelvis extended to the muscular structures of the uterus and the sigmoid colon of a 72 year old patient, what made it an exceptional case. The diagnosis of these secondary localizations is a diagnosis of elimination, almost always post-operative, made on the histopathological and immunocytochemical study of the surgical specimen, supported by cytogenetics, even molecular biology

  • Malignant melanoma or cutaneous lymphoma or lymphoma of the skin accounts for 1% of all cancers and has an incidence of 3% - 7% in the female genital tract, most of the cases being described in the vulva and the vagina

  • It is a malignant tumor of the skin or the mucous membranes, developed from melanocytes, some cases of primitive localizations were described in pelvic

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Summary

Introduction

Malignant melanoma or cutaneous lymphoma or lymphoma of the skin accounts for 1% of all cancers and has an incidence of 3% - 7% in the female genital tract, most of the cases being described in the vulva and the vagina. It is a malignant tumor of the skin or the mucous membranes, developed from melanocytes, some cases of primitive localizations were described in pelvic. Rare cases of genital metastases were described in the literature [3] [4] [5] Their retro-uterine localization with extension to myometrium and sigmoid is exceptional, arousing the interest of such an observation. The diagnosis is based on a standard histological examination supplemented by immunohistochemical studies, cytogenetics and sometimes analysis in molecular biology, starting from a representative sample of the tumor

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