Abstract
Myocardial protection in neonates and infants during heart surgery is still a matter of considerable debate. Multiple centers around the world have devised their own methods. Despite multiple claims of superiority of one method over another, there is no firm evidence in favor of one method over another and considerable research work is required in this field. This review summarizes the past, present and future of myocardial protection in children.
Highlights
Surgical management of cardiac defects had remained a great challenge to the surgeons for the greater part of the twentieth century
Another meta-analysis by Guru et al [50] concluded that in adult hearts blood cardioplegia provided superior myocardial protection compared to crystalloid cardioplegia
A hot shot is warm, K+ containing cardioplegia solution enriched with substrates like histidine, glutathione aspartate which is given prior to releasing the aortic cross clamp and provides to heart along with oxygen and substrates for myocardial recovery.The immature heart is less tolerant to reperfusion injury compared to adult heart [53]
Summary
Myocardial Protection in Neonates and Infants: What have we Learnt? Choudhary and Balram Airan Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India. Received Date: March 07, 2015, Accepted Date: July 01 2015, Published Date: July 10, 2015
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