Abstract

Aim. To determine the effects of stress at workplace on the risks (HR: hazard ratio) of development of myocardial infarction and stroke in open population of 25-64-yearold women in Russia/Siberia (Novosibirsk). Material and methods. Random representative sample of 25-64-year-old women (n=870) was examined in a framework of WHO MONICA-Psychosocial program in one of Novosibirsk districts. Stress at workplace was studied by using the Karasek scale; attitudes to work and prophylactic exams were studied by using the scale of “Knowledge and attitude towards one’s own health” of WHO MONICA-Psychosocial program. During 16 years (1994-2010), all first-time cases of myocardial infarction and stroke were studied in the cohort based on the WHO program of Register of Acute Myocardial Infarction and all available documentation. Cox regression model was used for determination of myocardial infarction and stroke risk over 16 years of follow-up. Results. Prevalence rate of high level of stress in open population of 25-64-yearold women was 31,6%. High levels of stress at work were associated with high levels of responsibility, inability to get rest at the end of workday, frequent professional dissatisfaction, and decreased working ability. For 16 years, HR was by 3,22 times higher for myocardial infarction (p<0,05) and 1,96 times higher for stroke (p<0,05) in women with stress at work. Rates of myocardial infarction and stroke were higher in married women who experienced stress at work, belonged to categories of managers and physical labor, and had high and low level of education. Conclusion. Prevalence of high level of stress at workplace is significant in open population of 25–64-year-old women in Russia/Siberia (Novosibirsk). In the presence of stress at workplace, HR of myocardial infarction and stroke were 2 to 3 times higher than without it. Social gradient affected HR of infarct and stroke.

Highlights

  • We studied the relationships between workplace stress and social characteristics of women who developed myocardial infarction (MI) and stroke

  • According to data of the fourth study of the European Working Conditions Survey conducted in the European Union countries in 2005, 20,3% of women report about the presence of stress at workplace and 31% of women believe that work affects their health [7]

  • In combination with inability to have rest at home after work, these observations explain the higher rates of cardiovascular events in married women experiencing workplace stress which was shown in the present study: about 70% of women with MI/ stroke and stress at work were in the category of “married”

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Summary

Objectives

The aim of the present study was to determine the prevalence rates of stress at work in an open population of 25-64-year-old women and to investigate the effects of stress on hazard ratios (HR) for myocardial infarction and stroke during the long-term period of observation (16 years)

Methods
Results
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