Abstract
IT was recently reported1 that the sulphydryl (—SH) agent, parachloromercuribenzoate (PCMB), causes superprecipitation of actomyosin gel. Masking of an —SH group appears to prevent interaction between ATP and some inhibitory site on the protein, thus enabling ATP to induce superprecipitation through reaction with another site. If this phenomenon is related to changes occurring in the actomyosin system during muscle activity, then —SH agents should be expected to produce contraction. Accordingly, several such agents were tested on skeletal muscle, and they were found to cause various types of contractile phenomena.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
