Abstract

Opinions are divided with respect to certain dermatoses associated with a form of atypical epithelial proliferation to which the name "dyskeratosis" was given by Darier in 1914. This dyskeratosis is observed in Bowen's, Paget's and Darier's diseases, in chronic roentgenray and radium dermatitis, in molluscum contagiosum, in senile keratoderma, in xeroderma pigmentosum and occasionally in various types of epithelioma of the skin. While Paget's disease of the nipple has long been regarded as a clinical and histologic entity, the identity of Bowen's precancerous dermatosis and of extramammary Paget's disease is often predicated on vague and indeterminate clinical and microscopic observations. <h3>DIAGNOSTIC ERRORS</h3> A number of cases appearing in the literature under such designations, as Bowen's disease, the Bowen type of epithelioma and extramammary Paget's disease, are in reality examples of peculiar forms of epithelioma, usually of the basal cell variety, but at times prickle cell and more rarely of the

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