Abstract

Introduction: Granular cell tumors are a rare form of soft tissue tumor often arising from the skin and subcutaneous tissues of the head, trunk, or extremities, although they rarely may arise within the colon or gastrointestinal tract.Case Report:We present a case of a 28 year-old female who initially presented with recurrent granular cell tumors of the stomach treated with endoscopic polypectomy. She eventually developed a metachronous lesion within the ascending colon and underwent a segmental colectomy. We present her treatment course, pathological findings, and review of the literature of this unique condition.

Highlights

  • Case PresentationAn otherwise healthy 28-year-old African American female presented to her gastroenterologist in 2006 for evaluation of vague gastrointestinal symptoms of abdominal cramping, burning, and epigastric pain

  • Granular cell tumors are a rare form of soft tissue tumor often arising from the skin and subcutaneous tissues of the head, trunk, or extremities, they rarely may arise within the colon or gastrointestinal tract.Case Report:We present a case of a 28 year-old female who initially presented with recurrent granular cell tumors of the stomach treated with endoscopic polypectomy

  • First described by Abrikossoff in 1926 [1], granular cell tumors are a rare family of soft tissue tumors

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Summary

Case Presentation

An otherwise healthy 28-year-old African American female presented to her gastroenterologist in 2006 for evaluation of vague gastrointestinal symptoms of abdominal cramping, burning, and epigastric pain. The pathology of the biopsy returned as a sub-centimeter granular cell tumor (GCT) (Figure 1) The remainder of her EGD, including esophageal visualization and antral biopsy for Helicobacter pylori, was negative. Cancer and Oncology Research 1(2): 52-54, 2013 excision of a 9mm submucosal nodule adjacent to the ileocecal valve histologically consistent with a GCT (Figure).No malignancy was identified within the nodule nor within the lymph nodes harvested at the time of surgery.

Discussion
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Treatment
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