Abstract

Lipoma is an uncommon soft tissue benign neoplasm of mouth. It is rarely in multiple locations on a single patient. This is a report of a 70-year-old black male patient with the complaint of multiple swellings on the tongue lasting 1 year. Physical examination revealed 3 well-delimited, yellow, smooth nodules located bilaterally on the border of the tongue. The main clinical hypothesis was amyloidosis. The patient presented controlled hypertension, diabetes, and any personal or family history of similar lesion. An incisional biopsy from 1 nodule was performed, and microscopic examination revealed an encapsulated proliferation of mature adipocytes, sometimes interweaving the muscle fibers, rendering the diagnosis of lipoma. The remaining lesions were excised, and the microscopic examinations were similar. The patient is well with no signs of relapse or recurrence. The present case highlighted the rarity of multiple classical lipomas occurring unassociated with lipomatosis or other systemic disease.

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