Abstract

Japanese folklore suggests a therapeutic capacity of the extract of the pine cone of Pinus parviflora Sieb, et Zucc. for gastric cancer. We partially purified the antitumor substances (Fr. VI and Fr. VII) by acid- and ethanol- precipitation from the NaOH extract (1). It was unexpectedly found that the replication of human immunodeficiency virus (HIV) was potently inhibited by these fractions (2, 3). We report here their structural analysis and ability to induce several kinds of interesting biological activities.

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